Postdoctoral Researcher position in the Laboratory of Cellular Proteostasis at International Institute of Molecular and Cell Biology in Warsaw – Poland

Summary

The International Institute of Molecular and Cell Biology in Warsaw invites applications for a postdoctoral researcher in the Laboratory of Cellular Proteostasis. The six‑month contract (extendable) focuses on the SONATA‑funded project "Nuclear protein quality control in neurodegeneration," aiming to validate CRISPR/Cas9 screen hits and study their roles in nuclear protein homeostasis using iPSC‑derived neurons. The position offers a gross salary of 9,700 PLN per month, additional bonuses, private medical care, and MultiSport membership. Candidates must hold a PhD in biology, biotechnology or biochemistry, have relevant laboratory experience, strong English communication skills, and at least one first‑author publication. The role is research‑only, with full support, training, and mentoring provided.

Key Facts

Department	Laboratory of Cellular Proteostasis
Position Type	Postdoc
Discipline	Biological Sciences (Biology)
Research Area	Nuclear protein quality control in neurodegeneration
Degree Required	PhD in biology, biotechnology, or biochemistry
Salary	9,700 PLN gross per month
Funding	EU programme grant (SONATA grant)
Contract Duration	Full employment contract initially for 6 months with a possible extension
Language	English
Deadline	2026-11-20
Required Documents	CV including full list of publications, Motivation letter with description of key achievements, Contact details (email and telephone) of at least two referees
Employer Address	4 Księcia Trojdena Street, 02-109 Warsaw, Poland
Employer Contact	E-mail: [email protected], Phone: 601159660

About the Project

The project investigates how protein quality control and the ubiquitin‑proteasome system operate in the mammalian nucleus, particularly in the context of neurodegenerative diseases. Building on a completed CRISPR/Cas9 high‑throughput screen, the researcher will validate candidate hits, characterize their mechanistic roles in nuclear protein homeostasis, and evaluate their functional relevance using human iPSC‑derived neurons and disease models.

Key Responsibilities

• Validate candidate hits from a CRISPR/Cas9 screen
• Conduct mechanistic studies on nuclear protein homeostasis
• Assess functional relevance in iPSC‑derived neurons and disease models
• Plan and execute experiments using cell culture, biochemical, flow cytometry, and confocal microscopy techniques
• Document work in an electronic laboratory notebook
• Present and discuss findings regularly

Required Skills

• Protein molecular biology and biochemistry techniques
• Mammalian cell culture, preferably including iPSCs
• Flow cytometry and confocal microscopy
• Strong written and oral English communication
• Presentation skills at international conferences
• Collaborative interdisciplinary teamwork
• At least one first‑author publication in a peer‑reviewed journal

Who Should Apply

Applicants who have earned a PhD in biology, biotechnology or biochemistry within the last seven years, possess hands‑on experience in protein biochemistry, mammalian cell culture (including iPSCs), and techniques such as flow cytometry and confocal microscopy, and have a first‑author publication in an international peer‑reviewed journal. Strong written and oral English skills, presentation experience at international conferences, and the ability to work collaboratively in an interdisciplinary team are also required.

Benefits

• Full employment contract initially for 6 months with possible extension
• Gross salary of 9,700 PLN per month
• 13th‑month salary bonus after six months
• Christmas bonus
• Reduced‑rate private medical care package
• Membership in the MultiSport programme
• Full technical, administrative and organizational support
• Access to courses, scientific training, peer support and academic mentoring

About the Employer

The International Institute of Molecular and Cell Biology (IIMCB) in Warsaw is a research institute dedicated to molecular and cellular biology. It hosts the Laboratory of Cellular Proteostasis, which focuses on protein quality control mechanisms and their relevance to neurodegenerative diseases.

Frequently Asked Questions

What is the application deadline?

20 November 2026

When does the position start?

1 January 2027 or later

Which documents must be submitted?

A CV with publications, a motivation letter, and contact details of at least two referees

Is the position funded?

Yes, it is funded by an EU programme (SONATA grant) with a salary of 9,700 PLN gross per month

Are there teaching obligations?

No, the position is 100 % research‑focused with no teaching duties