Research Associate / Bioinformatician in Institute of Molecular and Clinical Ophthalmology Basel – Switzerland

Summary

The Institute of Molecular and Clinical Ophthalmology Basel seeks a Research Associate/Bioinformatician to lead quantitative analysis of large‑scale retinal imaging datasets. The role involves developing deep‑learning derived features, statistical and machine learning models of disease progression, and pipelines for patient stratification. Collaboration with clinicians will translate computational findings into trial design and endpoint development. Candidates must hold an MSc or PhD in a quantitative field, possess strong Python programming skills, and have experience with high‑dimensional biomedical data. The position is full‑time, based in Basel, and offers access to state‑of‑the‑art facilities, family‑friendly policies, subsidised meals, childcare support and sports facilities. Applications are submitted via the IOB recruiting portal referencing IOB 173.

Key Facts

Department	Retinal and Macular Degeneration Clinical Research Group
Position Type	Full-time
Discipline	Bioinformatics
Research Area	Retinal imaging and disease progression modeling
Degree Required	MSc or PhD

About the Project

The project focuses on quantitative analysis of retinal imaging data (OCT, fundus photography) using deep‑learning derived features. The researcher will develop and validate statistical and machine‑learning models of disease progression, build patient stratification pipelines, and work with clinicians to integrate computational insights into clinical trial design and endpoint selection.

Key Responsibilities

• Analyze large‑scale retinal imaging datasets using deep‑learning derived features
• Develop and validate statistical and machine‑learning models of disease progression
• Build patient stratification and phenotyping pipelines
• Collaborate with clinicians to translate findings into trial design and endpoint development
• Contribute to publications and present at international conferences

Required Skills

• MSc or PhD in a quantitative field (computational biology, bioinformatics, etc.)
• Strong Python programming and reproducible workflow development
• Experience with high‑dimensional biomedical or imaging datasets
• Ability to communicate technical methods to computational and clinical audiences
• Evidence of independent quantitative research (thesis, publication, software)

Who Should Apply

Applicants with an MSc or PhD in computational biology, bioinformatics, computer science, biomedical engineering, physics, statistics or a related quantitative discipline, strong Python programming abilities, and experience handling high‑dimensional biomedical or imaging data should apply.

Benefits

• State‑of‑the‑art facilities in an international research environment
• Family‑friendly policies and practical support
• Subsidised meals and childcare support
• Access to university sports facilities (Unisport)

About the Employer

The Institute of Molecular and Clinical Ophthalmology Basel (IOB) combines basic and clinical research to advance understanding of vision and its diseases. It hosts the Retinal and Macular Degeneration Clinical Research Group, which conducts translational research on retinal structure, function, and therapy response, collaborating with over 30 international partner sites across Europe, North America, and Asia.

Frequently Asked Questions

How many positions are available?

One position.

What is the application deadline?

Not specified.

How can I apply?

Through the IOB recruiting portal, quoting reference IOB 173.