Postdoctoral Researcher in Pancreatic Organoids and Type 2 Diabetes (NCN OPUS Project UMO-2024/53/B/NZ4/03103), Adam Mickiewicz University, Poznań, Poland

Summary

The Institute of Molecular Biology and Biotechnology at Adam Mickiewicz University seeks a postdoctoral researcher to join an NCN‑funded OPUS project on pancreatic organoids and type 2 diabetes. The fellow will investigate disease‑related changes using multi‑omics approaches, including stem‑cell differentiation, genome editing, single‑cell RNA sequencing, proteomics, lipidomics, functional assays and imaging. The position is full‑time, fixed‑term for six months with possible extension to February 2029, offering a gross monthly salary of PLN 8,987 and a range of social benefits. The role involves collaboration with internal teams and partners at the University of Helsinki, and provides opportunities for training, seminars and international conference participation.

Key Facts

About the Project

The project aims to elucidate alterations in pancreatic organoids derived from type 2 diabetes patients by applying state‑of‑the‑art multi‑omics techniques. Researchers will differentiate human stem cells into pancreatic beta cells, generate organoids, perform advanced genome editing, conduct single‑cell RNA sequencing, proteomics and lipidomics, and carry out functional assays and imaging. Findings are expected to inform the development of cell‑ and gene‑based therapies for diabetes.

Key Responsibilities

• Study changes in pancreatic organoids from type 2 diabetes patients using multi‑omics techniques
• Differentiate human stem cells into pancreatic beta cells and produce organoids
• Perform advanced genome editing during differentiation
• Conduct single‑cell RNA sequencing, proteomics and lipidomics analyses
• Carry out functional assays and microscopic imaging
• Collaborate with internal team and external partners, including short‑term internships

Required Skills

• PhD in molecular biology, cell biology, developmental biology or biochemistry
• Hands‑on experience in multi‑omics analyses
• Knowledge in molecular biology, cell biology and bioinformatics
• Publication record
• Scientific curiosity, high motivation, independence and reliability
• Ability to work in a team
• Fluent written and spoken English
• Compliance with NCN OPUS competition criteria
• Compliance with Article 113 of the Law on Higher Education and Science
• Experience in stem cell differentiation, pancreatic physiology, CRISPR/Cas9 genome editing or single‑cell RNA sequencing (asset)

Who Should Apply

Applicants should hold a PhD in molecular biology, cell biology, developmental biology or biochemistry, have hands‑on experience with multi‑omics analyses, and possess a solid background in molecular biology, cell biology and bioinformatics. A strong publication record, high motivation, independence, reliability, teamwork skills and fluent English are required. Candidates must be able to comply with NCN OPUS competition criteria and Polish higher‑education regulations.

Benefits

• Fixed‑term full‑time contract with possible extension
• Gross monthly salary of PLN 8,987
• Friendly, dynamic and supportive work environment
• Professional training, thematic seminars and conference participation
• Flexible working hours
• Funding for language learning and co‑financing of training courses
• Additional days off for education
• Life insurance, pension plan, savings and investment fund, preferential loans
• Healthcare package and "13th" salary
• Leisure‑time funding and subsidies for children’s vacations
• Support for employees with disabilities

About the Employer

Adam Mickiewicz University’s Institute of Molecular Biology and Biotechnology, Faculty of Biology, hosts the Laboratory of Stem Cell Biology and Regenerative Medicine, a leading scientific institution in Poland that conducts cutting‑edge research in molecular and cellular biology.